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The vice president concluded Wednesday that his window "has closed" on running for president. He's had a long and colorful career. Here are some serious (and not so serious) things to know about him.

"When we come across these kids, or some are older than just kids, then deport them," Joe Arpaio told NPR. "They can do a lot of good in those countries."

Biden wants to change the filibuster to one in which a senator actually has to talk for potentially hours on end. Many Democrats hope that could ease passage of some of their priorities.

He doesn't cut the profile of a member of "The Resistance," but Bolton's opposition to a pressure campaign to get Ukraine to investigate conspiracy theories may pit him against his former boss.

With Democratic leader Harry Reid's victory in Nevada, Republican hopes for taking over the Senate have faded — even as Reid's leadership will be put to the test in a more narrowly divided Senate with a handful of Tea Party members. Republicans have picked up six seats — in Indiana, Illinois, Arkansas, North Dakota, Pennsylvania and Wisconsin.

Voters across the country cast ballots in congressional races. Republican incumbents survived strong challenges, among them Senator Pat Toomey of Pennsylvania.

The Republican nominee has landed in controversy after controversy. Thursday night, after shaking up his campaign, Trump acknowledged regret for sometimes causing "pain" with his words.

Democrat Jon Ossoff came close to winning a district that has been in GOP hands since the 1970s. It was Tom Price's district before he became HHS secretary. It was also Newt Gingrich's district.

Supreme Court nominee Judge Sonia Sotomayor said Wednesday that neither President Obama nor any member of the White House staff asker her substantive questions about abortion or any other issue prior to her nomination. This was the second long day of questioning for Sotomayor, with more expected Thursday.

Streamers have been removing content from their platforms lately — and they're canceling series after just one season. "It's soul-crushing," says one creator. "There is nothing we can do."

A grand jury in Texas declined to indict rapper Travis Scott for a deadly crowd surge at his concert in 2021. NPR's Scott Simon talks with the Houston Chronicle's Joey Guerra about the incident.

Over 50 years ago, a poet was found dead in Karachi, Pakistan. The incident triggered a media frenzy, but the murder mystery faded from memory — until now.

Ravi Shankar took Indian classical music to world stages and introduced the sitar to Western audiences. His influence can still be felt today, 100 years after his birth.

The declining share of U.S. doctors in adult primary care is about 25% — a point beyond which many Americans won’t be able to find a family doctor at all.

NPR's Leila Fadel talks to Indian American writer Prachi Gupta about how chasing the American dream destroyed her relationship with her parents. Her new book is: They Called Us Exceptional.

Ukraine calculates the agony of war in many ways. Lives lost, homes destroyed, families turned into refugees. There's also trauma that's harder to measure — the collective mental health crisis.

Senate Banking Committee Chairman Christopher Dodd unveiled a bill to revamp U.S. financial regulations. The plan calls for a consumer protection agency within the Federal Reserve and gives the central bank enhanced powers. Dodd discusses the measure.

Hundreds of Big Bend residents lost their home last week to Idalia, with Horseshoe Beach taking one of the hardest hits of all. Officials estimate it may take up to two weeks to restore power to the area.

Authorities say it is still not safe enough to allow residents and others back into the burned areas in and around Lahaina, where an estimated 2200 structures were damaged or destroyed by the fires.

The billionaire real-estate mogul's Crippled America, like any presidential campaigner's book, might be about publicity more than substance.

Sedaris' Theft by Finding is a collection of excerpts from those diaries. In it, he revisits major turning points, like how he met his longtime boyfriend and his decision to stop drinking.

The pandemic was hard on working women, but they've come roaring back into the labor force. The share of working-age women who have jobs or want one hit an all-time high in June.

Four years after user fees were imposed to speed up the review of generic drug applications by the Food and Drug Administration, more than 4,000 generics remain in limbo.

Public professional Facebook pages focused on medicine are catching on. But doctors aren't ready to share vacation photos and other more intimate details with their patients.

Rachel Martin talks to Republican Sen. Cory Gardner of Colorado about his reaction to President Trump agreeing to meet North Korea's leader. The invitation was facilitated by South Korean diplomats.