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NPR's Noah Adams talks with NPR's Brenda Wilson about the current state of the global HIV-AIDS epidemic, new strategies for treating the illness and the prospect of a cure.

NPR's Robert Siegel talks former White House adviser David Gergen, who expects that Condoleezza Rice will very clearly represent the president's thinking if she is confirmed as secretary of state.

In the year of the famed sleuth's 150th birthday, Norton has published "The New Annotated Sherlock Holmes." With more than 700 illustrations and 1,000 annotations, the two-volume set is the definitive edition of the Holmes canon. NPR's Liane Hansen talks to editor Leslie Klinger.

A U.S. senator is calling for the resignation of U.N. Secretary-General Kofi Annan. Annan is being accused of fraud and lack of oversight in the Iraq oil-for-food program. Annan's battle to keep his job nearly overshadows plans for renovation and expansion of U.N. headquarters in New York City. NPR's Tony Cox talks with Ian Williams, a U.N. correspondent for The Nation magazine, and Mike Aiello, a staff writer for Forbes magazine, who has investigated the oil-for-food program at length.

The holiday season can be tough on a budget. With a few hints and some advice on favorite gifts, it's easier not to overspend.

NPR's Noah Adams talks with Reuters correspondent Oliver Bullogh about popular reaction in Ukraine's eastern provinces to the former Soviet Union satellite nation's current political crisis. Bullogh returned Tuesday from the eastern city of Danetsk, where there is widespread support for pro-Russia candidate Viktor Yanukovych, to the capital of Kiev, where tens of thousands of protesters have held a week-long vigil in support of pro-European candidate Viktor Yushchenko.

NPR's Alex Chadwick talks to Martin Regg Cohn, Asia correspondent for The Toronto Star, about the legacy of the deadly chemical plant accident in Bhopal, India 20 years ago that killed as many as 15,000 people. Two decades after 40 tons of methyl isocyanate leaked from the Union Carbide pesticide plant, the effects of the disaster are still evident.

A car bomb explodes outside a mosque in northern Baghdad, killing at least 14 people. In southern Baghdad, insurgents attack a police station, killing at least six police officers and freeing more than 50 prisoners. Both attacks came around dawn. NPR's Mike Shuster reports.

HBO's biopic The Life and Death of Peter Sellers debuts on the pay-cable network Sunday. Geoffrey Rush plays the great British comic. To celebrate, NPR's Scott Simon and New York Times critic Elvis Mitchell help movie fans brush up on some of Sellers' finest screen moments.

Among the week's stories: American teens are waiting longer before starting to have sex; a new test for treating breast cancer; and a faster drug to treat tuberculosis.

President Bush selects Nebraska Gov. Mike Johanns to succeed Ann Veneman as secretary of agriculture. Johanns is a popular Republican with lifelong ties to agriculture. Also, John Danforth, U.S. ambassador for the United Nations, resigns. NPR's Andrea Seabrook reports.

NPR's Carrie Kahn reports on the life and death of Lance Cpl. George J. Payton, a young man from the Southern California town of Culver City who died in combat in Fallujah. Payton loved to laugh, party and listen to the music of the late hip-hop icon Tupac Shakur.

The city of Fallujah is now in the control of U.S. and Iraqi forces. But observers say there's much more to the insurgence than just Fallujah, and the problem of holding timely elections remains. Hear NPR's Tom Gjelten and Anthony Cordesman of the Center for Strategic and International Studies.

John Fogerty, the creative force behind the '60s rock group Creedence Clearwater Revival, has released his sixth solo album. It's his first CD of new material in seven years. NPR's Scott Simon talks with Fogerty about his life and music.

NPR's Laura Sydell reports on a company called -- no kidding -- Genetic Savings and Clone, that's developing a process to genetically clone cats. Though some scientists are skeptical, several pet lovers are willing to spend a reported $50,000 for the procedure.

NPR'S Bob Mondello reviews the new film by Pedro Almodovar's new film, Bad Education Mondello says the film -- on its surface -- is about abuse and sexual transgression, but it is also a film about filmmaking.

Marta Gomez's new CD, Cantos de Agua Dulce (Songs of Sweet Water), encompasses the varied rhythms of Latin America and Spain. But her songs also comment on many social issues, from Europe to South America. Hear NPR's Steve Inskeep.

President Bush has pledged to try to simplify the nation's tax code. David Wessel, deputy Washington bureau chief of The Wall Street Journal, talks about what might be involved in the proposed tax reform. Hear Wessel and NPR's Steve Inskeep.

NPR's Jennifer Ludden talks with Frontline reporter Lowell Bergman about The Secret History of the Credit Card, a new documentary by PBS and The New York Times. The film traces the rise of America's credit card industry and raises concerns about some if its business practices.

After troops bound for Iraq asked Defense Secretary Donald Rumsfeld pointed questions about armor shortages, Pentagon spokesman Lawrence DiRita defended the military's handling of the problem. NPR's Vicky O'Hara reports.

In the latest Politically Speaking column, Senior Washington Editor Ron Elving explains how moral values became the "big story" of the 2004 election.

Are street shrines meaningful memorials, or a public menace? Shirley Skeel reports on street shrines in Oakland, Calif., that honor victims of gang violence -- and how the decision of local police to remove the shrines has divided that community.

Heavy U.S. air and artillery bombardment continued Monday night in the Iraqi city of Fallujah, as Marine and Army battalions began entering the city. Hear NPR's Renee Montagne and NPR's Anne Garrels.

President Bush's first term brought some of the largest tax cuts in U.S. history. In his second term, he wants to revamp the tax code altogether; some in Congress favor a tax based on what people spend, not on what they earn. NPR's Andrea Seabrook reports.

The United States continues to send weapons and machinery to Ukraine to help in its war against Russia. The increase in shipments includes much needed howitzers from a U.S. base in Delaware.