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NPR's Ari Shapiro speaks with Charles Lister of the Middle East Institute about what the U.S. strike in Syria Wednesday night means for the future of ISIS.

NPR's Ari Shapiro talks with Chiquita Brooks-LaSure, administrator for the Centers for Medicare and Medicaid Services about the Supreme Court ruling on the vaccine mandate for health care workers.

When Los Angeles Mayor Antonio Villaraigosa was elected in 2005, not only was he seen as a rising star in the Democratic Party, he also was L.A.'s first Latino mayor in more than a century. As Villaraigosa prepares to leave office, many Latino politicians and leaders are assessing the two candidates vying to succeed him. And while one has Mexican ancestry, neither candidate is seen as a product of L.A.'s Latino community or political establishment.

As slow-moving trade talks with China resume this week, NPR's Ari Shapiro speaks with Wendy Cutler, a veteran U.S. trade negotiator.

Thousands of Cuban migrants are stuck at the Costa Rica-Nicaragua border. Nicaragua, a close ally of Cuba, won't let the migrants enter into its country to continue north to the United States.

For the first time in more than a decade, overdose deaths are falling sharply in the U.S. Experts say the improvement is so dramatic they're unsure why it's happening - but they're looking for clues.

In the U.S., possessing and selling marijuana is a federal crime, so banks have ignored this emerging market. In Canada, financial institutions are beginning to back corporate cannabis producers.

Noel King talks to Matt Haverstick, an attorney representing 2 Catholic dioceses in Pennsylvania, about the grand jury report on sexual abuse of children by priests in six of the state's dioceses.

Israel is calling up more troops as it returns to war again in Gaza, but fewer military reservists are willing to report for duty this time, complicating Israel's war plans.

Thousands of students without legal status are back in Texas university classrooms, but this time having to pay as foreign students, after the in-state tuition law was halted by a June court ruling.

Canada and Mexico struck last-minute deals with President Trump to pause 25% tariffs on a broad range of their goods.

A new program in Oregon lets drivers upload photos of roadkill, which officials say can help them identify dangerous hotspots and reduce the number of animals killed. It's one of several such programs that have sprouted up to protect wildlife from cars.

A green card holder's arrest for his activism raises questions about the rights of legal permanent residents. NPR talks with National Foundation for American Policy Executive Director Stuart Anderson.

NPR's Ailsa Chang speaks with Oregon Sen. Jeff Merkley, a member of the Democratic Party, about provisions in the debt ceiling bill approaching a Senate vote.

Oliver Darcy, author of Status, a nightly newsletter about the corridors of media power, explains ABC's decision to take Jimmy Kimmel off air following his comments on the killing of Charlie Kirk.

Looking to be more active in the new year? Host of NPR's Life Kit Marielle Segarra explains how to build movement into your hectic schedule and stay motivated.

Looking to be more active? NPR's Life Kit gives tips for fitting in exercise into a hectic schedule and stay motivated to move with research-backed strategies.

People in the Deep South are getting a rare winter wonderland today. It's snowing where it almost never does: on beaches, in the French Quarter, and even in Florida.

This week, Iran executed a man linked to nationwide protests that have been going on for months after what human rights groups call a "sham trial." Will it cause anti-regime protesters to back down?

People in the Gaza Strip recount the harrowing stories of the weekend's fierce fighting between Israel and militants — and look to resuming their stressful, precarious day-to-day.

NPR's Leila Fadel speaks with Democratic Rep. Rosa DeLauro of Connecticut about Pentagon spending on the U.S. war against Iran.

After a rapid jump in recent years, rents have begun to level off around the country. And in some areas, rents are even falling.

Democratic primary voters in Colorado delivered some upsets Tuesday night, signaling they want a change from establishment candidates. Results from the state's primary also set up a key House race.

In Portland, Ore., a local nonprofit collects fresh food from restaurants, farms, businesses, and events that would otherwise be thrown away. The group then redistributes it to people in need.

ICE says agents detained more than 200 people during a few days of concentrated effort in Maine. Some of those people are now being released.