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Watch 25 of the year's greatest, most surprising Tiny Desk performances, featuring just a sampling of the gifted artists who passed through NPR Music's office this year.

For more than 45 years, the legendary John Prine has written some of the most powerful lyrics in the American music canon. He brings some of his best to this unforgettable Tiny Desk performance.

It might be the best product in the world, but that doesn't mean people will try it. What does it take to get consumers to try something new — like toothpaste tablets?

A Steinbeck scholar says Murder at Full Moon, a mystery about a series of brutal murders that appear to be the work of a werewolf, should be available to all. Steinbeck's estate disagrees.

Hear the elusive avant-garde pianist debut a new piece, etched in shimmering chords and dark, lamenting octaves.

Pathogens can blossom from an outbreak into a pandemic because they "exploit our interconnectedness and expose our inequities and divisions," the World Health Organization's leader says.

Aoife O'Donovan, Sarah Jarosz and Sara Watkins are bound by a love for bluegrass, chamber music, jazz, storytelling and singing.

Watch the ambitious countertenor sing music that spans more than 250 years, connecting the dots between David Byrne, George Frideric Handel and Philip Glass.

USF scientists say they're seeing a decline in the amount of nutrients from the original release in late March.

The positivity rate for new cases of COVID-19 was at 3.75% of tests returned Monday. That is well below the rate where the numbers of cases are considered to be accelerating.

NPR's Ari Shapiro talks with Hozayfa Yazji of the Norwegian Refugee Council about the children who have been killed in Gaza — some of whom had been receiving therapy for trauma from prior conflicts.

Most big city marathons were called off last year. Now that pandemic restrictions have eased, major marathons are planned for later in 2021 in cities including New York, Boston and Chicago.

A first-hand experience with racism led two Asian American high schoolers to create an online magazine that documents what they go through.

The National Restaurant Association is recommending to its members that employees continue to wear masks until the government clarifies how the guidance applies to a requirement to keep workers safe.

The new speedrunning game from Detroit developer Aerial_Knight combines a Black cyberpunk aesthetic with clear, compelling mechanics for a game you'll want to play over and over again.

The third season of Netflix's show, Master of None drops on Sunday. The show has changed focus from star Aziz Ansari following an allegation against him of misconduct on a date.

A new women's team is aiming to make history at this year's Indianapolis 500 with a woman owner, driver and crew members. In more than 100 years, only nine women drivers have competed.

Eleven years ago, a now-deceased millionaire hid a treasure and published a riddle that would help hunters find it. The chase spawned partnerships, marriages, but also burglary and even deaths.

Alden Global Capital is poised to win a shareholder vote to assume full ownership of Tribune Publishing – including the Chicago Tribune, the New York Daily News, and other storied metro papers.

The jokes come fast and furious in this Hulu series about a D-list supervillain (voiced by co-creator Patton Oswalt) struggling to keep it together.

The administration is now caring for almost 20,000 migrant children — most of them in emergency shelters. Lawyers argue that the shelters are a violation of what's called the Flores agreement.

Isaiah Acosta was born with life-threatening health issues. Now 21, he's done far more than beat the odds. At StoryCorps, his mother Tarah told him, "You want to do it all, whether it's scary or not."

Two low home appraisals spurred a Black woman in Indianapolis to administer her own fair housing test. The result led her to file a complaint alleging housing discrimination.

Some activists are sitting out protests after deadly incidents around the country. Others say they are not deterred but are taking extra safety precautions.

Twenty-five years after wolves were reintroduced to Idaho, state lawmakers want most of the animals killed, despite different advice from wildlife managers.