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Dozens of Republican state officials are suing over the White House's COVID-19 vaccine mandate that they say is unconstitutional and threatens business.

President Biden is taking questions from reporters on his top foreign and domestic priorities after talks with world leaders at the G-20 in Rome — and just ahead of the U.N. climate summit.

Steve Inskeep talks with Senate Conservatives Fund President Ken Cuccinelli, who is threatening to recruit conservative challengers to Republicans who vote against repealing the Affordable Care Act.

NPR's David Folkenflik discusses the offseason lockout negotiations with baseball analyst and former player Doug Glanville.

Rameshchandra Patel got COVID-19 early on in the pandemic, when little was known about the virus. His son, Suhash Patel, shares the guiding principles of life his father left as notes in a textbook.

NPR's Steve Inskeep talks to Dr. Anthony Fauci, the nation's top infectious disease expert, about the omicron variant, and how the U.S. should respond to its spread.

Congress faces a Friday deadline to keep federal agencies funded and avoid a partial shutdown, while Democrats push to pass the remainder of President Biden's spending agenda.

A raft of travel restrictions are being imposed by nations around the world as they scramble to slow the variant's spread.

With a top Trump-appointed banking regulator stepping down, consumer financial protection groups say the new head of the FDIC should crack down on lenders charging interest rates of 100% or more.

How do artists these days think about their work in our social media world? Sites like Instagram and YouTube are changing the way art is consumed, marketed and made.

President Biden is having a video call on Tuesday with Russian President Vladimir Putin amid growing concern about Russian troops amassed on the Ukraine border.

NPR's Mary Louise Kelly speaks with Kentucky state Rep. Attica Scott about the indictment of the former Louisville police officer in the shooting death of Breonna Taylor.

House Democrats will hold a conference call Monday to begin strategizing how they will respond to the conclusions in the special counsel's report on Russian interference and President Trump.

Scottie Scheffler continued his dominating year on the golf course with his first major championship at the Masters. His victory came as Tiger Woods made his return to competitive golf.

Retired Coast Guard Commander Stephen Flynn talks with Robert Siegel about a Dubai-based company's potential operating rights at major U.S. ports. Flynn says that the United States needs to bolster security at its shipping ports.

The Pentagon's release of documents detailing the hearings of Guantanamo detainees has cracked open a window into the government's top-secret world. The 5,000 pages offer unedited transcripts that include names and stories from some of the prisoners at the base. The documents were released in response to a Freedom of Information Act request by the Associated Press.

The people of New Orleans have re-elected Mayor Ray Nagin to guide their city through its continued recovery from Hurricane Katrina. Nagin's new term begins May 31, one day before the opening of a new hurricane season. Political analyst Greg Rigamer talks to Debbie Elliott about Nagin's victory and the direction he plans to steer the city.

At its national gathering in Chicago, the AFL-CIO tries to adjust to the desertion of two of its largest members: the Teamsters and the Service Employees International Union. Robert Siegel talks with Richard Trumka, Secretary-Treasurer for the AFL-CIO.

Syria's president, Bashar Al Assad, has called for reforms in Syria's state-controlled media. The system has opened up for privately owned newspapers and magazines. Arab governments know that the satellite television revolution makes it harder for tightly controlled state media to attract audiences, but reforming the system takes reforming individuals.

In the latest Politically Speaking column, NPR Correspondent Peter Overby wonders whether President Bush or John Kerry will opt out of $74 million in public campaign financing.

Sean Combs, known as "Diddy" to his fans, has released his first album in five years. The rap star and entrepreneur has a net worth of more than a quarter of a billion dollars. He hopes to add to his wealth with his new CD Press Play.

Hurricane Fiona's flooding washed out bridges and roads in several mountain communities in Puerto Rico. In Orocovis, the local government is scrambling to repair roads to hundreds of families.

From bagels to honey cake, these are a few suggestions from cooks and food enthusiasts for breaking the fast after the most solemn Jewish holiday. Also, read tips for preparing for the fast.

After record deforestation and environmental deregulation in the past few years, the result of the Brazilian election could very well determine the fate of the Amazon rainforest.

Williams, 40, and Federer, 41, have both announced in short succession their plans to retire, leaving the tennis world without two of its most iconic players.