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In the United States, an orphan disease is one that affects fewer than 200,000 patients. These conditions often involve chronic pain or fatigue, and can be controversial and difficult to diagnose. Yet they affect around 30 million Americans. Author Laurie Edwards is one such patient.

NPR's Ailsa Chang talks with Vivian Yoon. Her new podcast K-Pop Dreaming is a personal and historical journey through Korean pop music.

Ryan Block, managing editor of Engadget.com, explains EMI's decision to allow consumers to download its music catalog through Apple's iTunes free of copy protection.

The rate of inflation in the U.S. rose to a little over 8% last month. That's the highest rate since 1981. With the cost of good and services up, it's putting a strain on many families.

Hogs for the Cause, a New Orleans-based charity known for its barbecue fundraisers, will renovate apartments to provide quarters to families while their kids receive care.

People who sustain a concussion can develop an unusual hearing problem. Their ears work fine, but their brain struggles to process sounds.

Each week, the guests and hosts on NPR's Pop Culture Happy Hour share what's bringing them joy. This week: Bono's memoir, the Philly Orchestra playing Dancing On My Own, and Tove Lo's Dirt Femme.

The Folger Shakespeare Library in Washington, D.C., is emerging from a four-year metamorphosis. Eighty-two copies of Shakespeare’s “First Folio” will be together on public display for the first time.

Each week, guests and hosts on NPR's Pop Culture Happy Hour share what's bringing them joy. This week: The Gilded Age podcast, food influencer Keith Lee, the show Bargain, and Madi Diaz's new album.

As NATO leaders gather for this week's summit in Turkey, Europe is preparing to shoulder more of its own defense. David M. Cattler of the Center for European Policy Analysis explains why.

Volunteer scientist spend their time tracking living things in the Great Smoky Mountains National Park. It's all part of an important science project.

Pop-culture writer Nathan Rabin introduces us to some obsessive fans in his new book, which chronicles his experience following the followers of the bands Phish and Insane Clown Posse.

In her debut novel, Iranian-American Sara Farizan tells the story of two teenage girls, secretly in love. Sahar faces a crisis when she discovers Nasrin is engaged, and considers gender-reassignment surgery as a way for them to stay together. Farizan speaks with NPR's Jacki Lyden about the book and her own struggle with her sexual orientation.

From roller coasters to virtual rides, Florida's theme parks have helped redefine family entertainment. With Disney experiencing its own struggles with…

Barry Manilow has just overtaken The King himself, Elvis Presley, for the most shows at Westgate Las Vegas Resort & Casino.

With the help of her son Lawrence Blume, Judy Blume has adapted her 1981 novel into a film. The widely beloved coming-of-age author speaks with NPR's Audie Cornish about turning the book into a movie, and how the themes in Tiger Eyes echo her own life.

Here is the full text of Gov. DeSantis’ 2020 State of the State address on Tuesday:OPENINGMr. Speaker, Mr. President, members of the House and Senate, and…

Chess grandmaster Daniel Naroditsky has died at the age of 29. NPR's A Martinez talks with reporter David Cox about the impact Naroditsky had on the chess world.

She has high kicked with the Rockettes at Radio City Music Hall, shared a stage with Jimmy Durante, managed a city department in Las Vegas and taught in…

President Biden will address the COP26 climate change conference. He will speak about the United States strategy to reach its climate goals, but he doesn't have any commitments in hand.

President Trump doubled down on his views of the impact of U.S. strikes on Iran nuclear facilities, and said he's warming up to NATO after attending a summit in the Netherlands.

The judge said the untraceable weapons could end up in the wrong hands. But it's unclear how effective the order is since some gun plans have already been online for four days.

Pope Leo XIV is heading to the central African nation of Cameroon with a message of peace for its separatist region and for talks with President Paul Biya.

Fulfilling the masculine dream of having arms like Goliath probably isn't worth the downside of steroid use. Vicarious satisfaction is probably better, as author Marc Acito discovers upon reading Gladiator, the autobiography of one-time American Gladiators star Dan Clark, known to television audiences as Nitro.

The tech investor dives into the lawsuit that thrust her into the national spotlight and the workplace conditions that prompted it. She says firms are largely applying "tepid diversity solutions."