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Progressive groups have threatened repercussions for Democrats who backed Obama's trade deal, but primary threats have been a GOP tactic of late. Plus, two big candidates kick off their campaigns.

It was a historic night at the Academy Awards for a truly distinctive and radical film set in the multiverse — with an almost all-Asian cast.

Secretary of State Condoleezza Rice is in the Georgian capital of Tbilisi with the goal of getting Russian combat forces out of the former Soviet country. Rice is carrying a draft cease-fire that requires Russia to withdraw combat troops and allows peacekeepers to remain in the flash-point separatist region.

Book critic Maureen Corrigan reviews Tad Friend's new memoir Cheerful Money: Me, My Family, and the Last Days of Wasp Splendor.

From 2015 to 2020, about 20 percent of the reported U.S. cases were in Florida, and 81 percent of those cases were in Central Florida, according to a research letter released by the CDC.

The president's move to spare the former White House aide from 2 ½ years in prison for lying and obstruction of justice in the CIA leak case has brought harsh criticism from Democrats who say the decision shows the administration's lack of accountability.

A new National Intelligence Estimate concludes that al-Qaida and the home-grown cells that claim allegiance to it pose a greater threat to the United States than they have in several years.

Treasury Secretary Janet Yellen opens a visit to China Thursday. Will her trip help thaw a frosty bilateral relationship?

A House panel has authorized subpoenas for White House adviser Karl Rove and other officials Wednesday, if they refuse to testify voluntarily. President Bush has said he would not make them available for testimony unless they appear in private, and not under oath.

Lt. Gen. David Petraeus is expected to take command in Iraq and oversee President Bush's new policy. A graduate of West Point, Petraeus commanded the fabled 101st Airborne Division during the invasion of Iraq and went on to become the top trainer for Iraqi forces.

Top national security officials announced Wednesday that Iran and Russia have obtained voter registration data and are trying to influence the U.S. presidential election.

Closing arguments are expected Friday in a trial against extremist Ammon Bundy. Idaho's largest hospital sued him for $7.5 million after armed protests he led prompted a major security response.

Janet Yellen visits China to try to ease tensions. Facebook's parent company launches Threads to compete with Twitter. Parts of a synagogue destroyed by Nazis are found in a Munich river.

Sen. Hillary Clinton has agreed to be President-elect Obama's nominee for secretary of state; New York Fed chief Timothy Geithner is in line to be treasury secretary; and New Mexico Gov. Bill Richardson is up for the top job at Commerce.

Sen. Barack Obama topped Democratic rival Hillary Clinton in Tuesday's Mississippi primary. Despite overwhelming support in the African-American community for Obama, exit polls showed that he lost ground with white voters in what turned out to be the most racially polarized vote so far.

Chinese leader Hu Jintao promises to make communist rule more inclusive and better spread the fruits of China's economic boom during a nationally broadcast speech to China's Communist Party congress.

U.S. agencies have produced a National Intelligence Estimate on Iraq. The good news is that it sees al Qaida in Iraq's capabilities reducing, but the political side is a different story.

In a bid to stave off the swell of home mortgage foreclosures, the Bush administration announces plans to freeze interest rates for up to five years for certain subprime mortgage holders. The plan comes amid reports that third-quarter home foreclosures surged to an all-time high.

Roland Burris, Illinois Gov. Rod Blagojevich's pick to fill President-elect Barack Obama's Senate seat, will be seated in the Senate. The Senate's two top Democrats, Harry Reid and Dick Durbin, dropped their opposition to Burris being seated.

In a significant policy change, the U.S. has concluded there can be no power-sharing government as long as Zimbabwe President Robert Mugabe is in power. A State Department official spent days meeting with regional leaders in an attempt to get them to get tougher on the 84-year-old leader.

One of the greatest quarterbacks in the history of professional football has died. Sammy Baugh, who played for the Washington Redskins, was 94. Nicknamed Slingin' Sammy, he transformed the quarterback position with his accuracy and long passing.

President Obama met Tuesday with Republicans and Democrats in Congress to discuss Afghanistan. The meeting comes as Obama debates whether to increase troop levels in Afghanistan, as called for by his top commander in the country, Gen. Stanley McChrystal.

A new Justice Department report says that politics illegally influenced the hiring of career prosecutors and immigration judges. The 140-page report issued Monday largely lays the blame on top aides to former Attorney General Alberto Gonzales.

Democratic presidential nominee Barack Obama has picked up the endorsement of former Secretary of State Colin Powell. The former Bush administration official broke with the Republican party Sunday. Obama told a rally in Fayetteville, N.C., that he was honored to have Powell's support.

The hurricane closed pharmacies and clinics for a week or longer. Floodwaters spoiled drugs. People who fled to other states couldn't get their prescriptions filled for HIV medicine.